Correlation between the magnitude of T wave inversion with IRA patency following thrombolysis in STEMI

摘要

Objective: This study was undertaken to correlate the magnitudeof T inversion following thrombolysis in acute STEMI with InfarctRelated Artery (IRA) patency.Background: Although many studies have demonstrated the associationbetween early T wave inversion after thrombolysis andangiographic patency, T wave inversion magnitude after successfullysis with resolved ST segment was further evaluated inrelation to IRA patency.Methods: This is a prospective observational study done duringthe month of April 2014 in tertiary care hospital. A total of twentypatients, age ranging from 32 to 60 yrs with anterior and inferiorwall STEMI who were treated with I.V streptokinase as per protocolon admission and predischarge coronary angiogram wasdone within 5 days of admission . Patient stratification was donebased on the depth and width of maximally inverted negative Twaves, ejection fraction and it was correlated with angiographicpatency of IRA.Results: Among the twenty patients, recanalised IRA was found in2 patients who had more broad and deeply inverted T waves inECG. In the remaining 18 patients, deeper inverted T waves in 12patients was associated with better patency rate of IRA(70% vs30%), lower peak CPK value (250+/_50 vs 400+/-100) better EF (50+/_10% vs 35+/_5%) than the 6 patients who had small inverted Twaves .Conclusion: Early T wave inversion as quoted earlier has goodcorrelation with IRA patency. Also some correlation was foundbetween quantum of T wave inversion with IRA patency. However,this was not linear and further studies are required.