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Characterization of Human Health Risks from Particulate Air Pollution in Selected European Cities

机译:欧洲部分城市空气中颗粒物污染对人类健康的风险特征

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The objective of the current study was to estimate health risk indexes caused by the inhalation of particulate matter (PM) by adult males and children using data sampled in three European cities (Athens, Kuopio, Lisbon). Accordingly, the cancer risk (CR) and the hazard quotient (HQ) were estimated from particle-bound metal concentrations whilst the epidemiology-based excess risk (ER), the attributable fraction (AF), and the mortality cases were obtained due to exposure to PM 10 and PM 2.5 . CR and HQ were estimated using two methodologies: the first methodology incorporated the particle-bound metal concentrations (As, Cd, Co, Cr, Mn, Ni, Pb) whereas the second methodology used the deposited dose rate of particle-bound metals in the respiratory tract. The indoor concentration accounts for 70% infiltration from outdoor air for the time activity periods allocated to indoor environments. HQ was lower than 1 and the cumulative CR was lower than the acceptable level (10 ?4 ), although individual CR for some metals exceeded the acceptable limit (10 ?6 ). In a lifetime the estimated number of attributable cancer cases was 74, 0.107, and 217 in Athens, Kuopio, and Lisbon, respectively. Excess risk-based mortality estimates (due to outdoor pollution) for fine particles were 3930, 44.1, and 2820 attributable deaths in Athens, Kuopio, and Lisbon, respectively.
机译:本研究的目的是使用在三个欧洲城市(雅典,库奥皮奥,里斯本)采样的数据估算成年男性和儿童吸入颗粒物(PM)引起的健康风险指数。因此,根据结合颗粒的金属浓度估算了癌症风险(CR)和危险商(HQ),而由于暴露而获得了基于流行病学的过量风险(ER),可归因分数(AF)和死亡率案例。到PM 10和PM 2.5。 CR和HQ使用两种方法估算:第一种方法结合了颗粒结合的金属浓度(As,Cd,Co,Cr,Mn,Ni,Pb),而第二种方法则使用了颗粒结合的金属在金属颗粒中的沉积剂量率。呼吸道。在分配给室内环境的时间活动期间,室内浓度占室外空气渗透的70%。尽管某些金属的个别CR超过了可接受的限值(10〜6),但HQ低于1并且累积CR低于可接受的水平(10〜4)。一生中,雅典,库奥皮奥和里斯本的可归因的癌症病例估计分别为74、0.107和217。在雅典,库奥皮奥和里斯本,由于微粒造成的基于风险的超额死亡率估算(由于室外污染)分别为3930、44.1和2820例归因于死亡。

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