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Application of the Vienna classification for Crohn’s disease to a single center from Brazil

机译:克罗恩病的维也纳分类法应用于巴西的一个中心

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BACKGROUND: Crohn’s disease is a chronic inflammatory disorder with diversity on its clinical presentation that may be observed from the varying age of onset of symptoms to the site of occurrence of the illness. There is a need for a replicable and uniform description of the disease allowing a comparison between distinct study populations. The 1998 Vienna classification characterizes patients according to three clinical aspects: age at diagnosis, location and disease behavior. AIM: To describe Crohn’s disease in patients from a reference center of Salvador, BA, Brazil according to the Vienna classification. METHODS: Between January and October of 2005, patients (n = 47) having at least one endoscopic and radiological examination of the intestine participated in this study. RESULTS: Most of the participants had the diagnosis of the disease when they were younger than 40 years old (70.2%) while an ileocolic location (38.3%) and the penetrating form (46.8%) were the most prevalent clinical presentation. The restricted location of the ileum (L1) was more frequent in nonstricturing, nonpenetrating disease (B1) while the ileocolic disease (L3) was more associated with the penetrating behavior (B3). CONCLUSION: In this study, differently from the first description of the Vienna classification, the large number of patients presenting a complicated stage of the disease can be attributed to the fact that it was carried out at a reference center, where many patients present with the disease at an advanced stage.
机译:背景:克罗恩氏病是一种慢性炎症性疾病,其临床表现多样,可从症状发作的不同年龄到疾病发生的部位观察到。需要对疾病进行可复制和统一的描述,以便在不同的研究人群之间进行比较。 1998年维也纳分类法根据三个临床方面对患者进行了特征描述:诊断时的年龄,位置和疾病行为。目的:根据维也纳分类法,描述来自巴西BA萨尔瓦多参考中心的患者的克罗恩病。方法:在2005年1月至10月之间,对接受肠内镜检查和放射学检查的患者(n = 47)进行了这项研究。结果:大多数参与者在40岁以下时就已诊断出该病(70.2%),而回肠位置(38.3%)和穿透形式(46.8%)是最普遍的临床表现。在非限制性,非穿透性疾病(B1)中,回肠的受限位置(L1)更为频繁,而回盲性疾病(L3)与穿透行为(B3)更为相关。结论:在这项研究中,与对维也纳分类的第一个描述不同,呈现出复杂疾病阶段的大量患者可以归因于在参考中心进行的事实,在该中心,许多患者表现出该疾病。疾病处于晚期。

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