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Melanoma: A new strategy to reduce morbidity and mortality

机译:黑色素瘤:降低发病率和死亡率的新策略

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Background Public awareness campaigns could address risk factors for melanoma to reinforce their sun protection message. The objective of this study is to prioritise risk factors associated with malignant melanoma (MM) to improve public awareness. Methods Design: A cross-sectional study with retrospective data analysis from 2004 to 2010. Setting: Western Australian Melanoma Advisory Service (WAMAS), a tertiary referral multidisciplinary organisation providing MM management advice. WAMAS data files were analysed with histologically confirmed cutaneous MM. Forty-seven patients had two or more melanomas, but the patient file was counted only once. Six MM data files with missing or incomplete information were excluded. Main outcome measures: The number of naevi, blood relatives with MM, and previous sunburns were the primary variables collected. Results The results showed that 70.9 per cent (268/378) had previous sunburn; 40.2 per cent (152/378) had multiple naevi; and 22.5 per cent (85/378) had a positive family history. In the 110 MM data files not associated with sunburn, multiple naevi and a positive family history represented 34.5 per cent (38/110) and 20.0 per cent (22/110), respectively. Conclusions The results confirm the findings of previous studies that multiple naevi and a positive family history are important risk factors associated with MM. We suggest that MM can be detected earlier and its mortality decreased by focusing on these high-risk groups who are not targeted by current public awareness campaigns.
机译:背景公众意识运动可以解决黑色素瘤的危险因素,以加强其防晒信息。这项研究的目的是确定与恶性黑色素瘤(MM)相关的危险因素,以提高公众的认识。方法设计:一项横断面研究,回顾性分析2004年至2010年的数据。环境:西澳大利亚黑素瘤咨询服务(WAMAS),这是一家提供MM管理建议的三级转诊多学科组织。 WAMAS数据文件用组织学确认的皮肤MM进行了分析。 47名患者患有两个或多个黑色素瘤,但患者档案仅计数一次。排除了六个丢失或不完整信息的MM数据文件。主要结局指标:收集的主要变量包括naevi的数量,MM的血缘亲属和以前的晒伤。结果结果表明,有70.9%(268/378)的人以前有晒伤; 40.2%(152/378)的资产净值倍数;有22.5%(85/378)的家族史为阳性。在与晒伤无关的110 MM数据文件中,多名naevi和阳性家族史分别占34.5%(38/110)和20.0%(22/110)。结论该结果证实了先前研究的发现,即多发性naevi和阳性家族史是与MM相关的重要危险因素。我们建议通过关注那些当前公众意识运动没有针对的高风险人群,可以更早地发现MM,并降低其死亡率。

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