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首页> 外文期刊>Asian Journal of Pharmaceutical and Clinical Research >CHRONIC HEART FAILURE CAUSES OSTEOPATHY OR IS OSTEOPATHY A FACTOR IN DEVELOPMENT OF CHRONIC HEART FAILURE?
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CHRONIC HEART FAILURE CAUSES OSTEOPATHY OR IS OSTEOPATHY A FACTOR IN DEVELOPMENT OF CHRONIC HEART FAILURE?

机译:慢性心力衰竭是导致骨病还是在导致慢性心力衰竭发展的因素?

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Objective: As their proportion rises in the aging population, cardiovascular disease and osteoporosis increasingly become significant health problems of the developed world, leading to reduced lifespan and substantial financial burdens, not the least because of complications and comorbidities associated with each disorder. This study investigates bone mineralization in patients with coronary heart disease (CHD) complicated by Stage I chronic heart failure (CHF). Methods: The study group consisted of 41 patients of both sexes with CHF Stage I against the background of CHD that with no severe comorbidities that could have potentially caused changes in bone tissue. Bone mineral density was measured using dual-energy X-ray densitometry of lumbar region of spine and proximal right femur. Results: Structural and functional changes in the bone of the lumbar spine were found in 75.9% of the patients with Stage I CHF caused by CHD. Osteopenia was diagnosed in 64.4% of the patients, while osteosclerotic bone changes were less frequent and found in 11.5% of the patients. 75.8% of the patients had structural and functional changes in the proximal segment of the right femur bone. In men with Stage I CHF against the background of CHD osteopenia was more often diagnosed in the proximal segment of the right femur, while in women it was found in almost equal proportion in the spine and hip. Conclusions: In both sexes with I Stage CHF against the background of CHD were diagnosed changes in bone mineralization, with osteopenia being the prevailing diagnosis.
机译:目的:随着人口的老龄化比例上升,心血管疾病和骨质疏松症日益成为发达国家的重要健康问题,导致寿命缩短和大量财务负担,这尤其是与每种疾病相关的并发症和合并症。这项研究调查了并发I期慢性心力衰竭(CHF)的冠心病(CHD)患者的骨矿化。方法:研究组由41名在CHD背景下患有CHF I期的男女患者组成,这些患者没有严重的合并症,可能导致骨组织改变。使用双能X射线光密度法测量脊柱和右股骨腰部的骨矿物质密度。结果:在75.9%的由CHD引起的I期CHF患者中,发现了腰椎骨骼的结构和功能变化。骨质疏松症的诊断率为64.4%,而骨硬化性骨改变的发生率较低,占11.5%的患者。 75.8%的患者在右股骨的近端部分具有结构和功能改变。在患有CHD的I期男性中,CHF背景下的骨质疏松症通常在右股骨的近端部分得到诊断,而女性在脊柱和臀部的比例几乎相等。结论:在患有CHD背景的I期CHF男女中,均被诊断出骨矿化变化,其中以骨质减少为主要诊断。

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