EVALUATION OF PHYTOCHEMICALS, ANTIOXIDANT AND CYTOTOXIC ACTIVITIES OF LAVANDULA ANTINEAE MAIRE ENDEMIC MEDICINAL PLANT FROM ALGERIA

摘要

The present study was designed to investigate the phytochemical screening, total phenolic and flavonoid contents,antioxidant and cytotoxic activities of Lavandula antineae Maire for the first time. Phytochemical screening revealed thepresence of anthraquinones, triterpenes, saponins, flavonoids, tannins, O-heterosides, C-heterosides. Total phenolic andflavonoid contents of the extracts varied between 12.49-262.35 mg GAE/g extract and 1.35-4.03 mg QE/g extract,respectively. The antioxidant activity was investigated using DPPH, reducing power and β-carotene/linoleic acid tests. Theresults indicated that ethyl acetate and diethyl ether fractions exhibited stronger activities than hydromethanolic crude extractand other fractions. In case of cytotoxicity assay, hydromethanolic extract was found to show good toxicity against brineshrimp nauplii (LC50= 13.72 μg/ml).