ANTIBACTERIAL AND PHYTOCHEMICAL ASSESSMENT ON VARIOUS EXTRACTS OF IPOMOEA PES-CAPRAE (L.) R. BRTHROUGH FTIRAND GC- MS SPECTROSCOPIC ANALYSIS

摘要

Objective: Ipomoea pes-caprae (L.) R.Br (IP) is a valuable medicinal plant, distributed in the tropics and subtropics regions.The present investigation was carried out to determine the antimicrobials as well as possible chemical components in IPby FTIR and GC-MS technique. Methods: The different solvent extracts (hexane, di-chloromethane, ethyl acetate and methanol) of the plant were tested for antibacterial activity against human pathogens. FTIR method was used to detect the characteristic peak values and their functional groups.GC-MS technique was used in this study to identify the components present in the extract. Results: The results highlighted that the methanol extracts exhibited remarkable antibacterial activity compared to other extracts against four out of the five human pathogens. FTIR method showed the specific peak for phenol, ester, alcohol etc. A total of nineteen biological compounds were isolated from the leaves of IP by GC-MS analysis among whichstigmasterol, 1-(+)-ascorbic acid, 2-6-dihexadecanoate and Phytol (3, 7, 11, 15-tetramethylhexadec-2-en-1-ol) are the major compounds. Conclusion: The study encourages this plant useas an alternative medicine for the treatment of diseases.