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Population-wide incidence estimates for soft tissue knee injuries presenting to healthcare in southern Sweden: data from the Sk?ne Healthcare Register

机译:瑞典南部医疗机构在膝关节软组织损伤方面的全人群发病率估计:Sk?ne Healthcare Register的数据

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Introduction Soft tissue knee injury is a well-established and potent risk factor for development of knee osteoarthritis. However, there is a paucity of epidemiological data from the general population. Our aim was to estimate the annual person-level incidence for a wide spectrum of clinically diagnosed soft tissue knee injuries, and their distribution by age, sex, and season. Methods In Sweden, in- and outpatient health care is registered using each individuals’ unique personal identifier including International Classification of Diseases (ICD) 10 diagnostic code(s) as determined by physicians’ clinical examination. For the calendar years 2004–2012, we studied the population in southern Sweden, Sk?ne region (approx. 1.3 million). We identified residents who had at least one visit to a physician with clinically diagnosed knee ligament, meniscal, or other soft-tissue injury (S80.0, S83 and all subdiagnoses). We then calculated the mean annual incidence over the 9-year period. As a secondary objective, we investigated potential seasonal variation. Results The annual incidence for males and females was 766 (95% CI: 742, 789) and 676 (649, 702) per 100,000 persons/year respectively. For males and females, the peak rate occurred in 15 to 19?year-olds (1698 per 100,000 men and 1464 per 100,000 women, respectively). In women, rates were lowest in the 25 to 34?year-old age range before rising again between the ages of 35 and 49?years. We found substantial seasonal variation, greatest in men, with peaks in March-May and August-October. Conclusions The incidence of clinically diagnosed soft-tissue knee injury peaks in adolescence and emerging adulthood. However, a range of knee injuries continue to occur across the adult lifespan including at ages when osteoarthritis is typically diagnosed and managed. The potential cumulative effect on osteoarthritis progression of these injuries may warrant further investigation. Electronic supplementary material The online version of this article (doi:10.1186/ar4678) contains supplementary material, which is available to authorized users.
机译:简介膝关节软组织损伤是公认的发展膝骨关节炎的有效危险因素。但是,来自一般人群的流行病学数据很少。我们的目的是估计各种临床诊断的软组织膝关节损伤的年人均发病率,以及它们的年龄,性别和季节分布。方法在瑞典,使用每个人的唯一个人识别码(包括国际疾病分类(ICD)10个诊断代码)对住院和门诊医疗服务进行注册,这些代码由医生的临床检查确定。在2004-2012日历年中,我们研究了瑞典南部斯科讷地区的人口(约130万)。我们确定了至少拜访过一名临床诊断为膝韧带,半月板或其他软组织损伤的医师的居民(S80.0,S83和所有亚诊断)。然后,我们计算了这9年期间的平均年发病率。作为次要目标,我们调查了潜在的季节性变化。结果男性和女性的年发病率分别为每100,000人/年766(95%CI:742,789)和676(649,702)。男性和女性的峰值发病率出现在15至19岁的年龄段(分别为100,000名男性中的1698名和100,000名女性中的1464名)。在女性中,发病率在25至34岁之间是最低的,然后在35至49岁之间再次上升。我们发现季节性变化很大,男性居多,在3月-5月和8月-10月达到峰值。结论临床诊断的软组织膝关节损伤的发生率在青春期和成年期达到峰值。但是,在整个成人寿命中,包括通常诊断和治疗骨关节炎的年龄段,膝盖受伤的情况持续发生。这些损伤对骨关节炎进展的潜在累积影响可能需要进一步研究。电子补充材料本文的在线版本(doi:10.1186 / ar4678)包含补充材料,授权用户可以使用。

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