Lipid Peroxidation in the Serum of Hypothyroid Patients(In Gorgan-South East of Caspian Sea)

摘要

This study was designed to determine if lipid peroxidation can be modified by hypothyroidism. Twenty eight subjects with hypothyroidism and 33 euthyroid subjects participated in this study (2007). Blood samples were collected and serum malondialdehyde, T3, T4 and TSH were measured. An increase in lipid peroxidation (expressed as Malondialdehyde, MDA) and TSH levels and also a decrease in T4 level were observed in the hypothyroid patients when compared with control groups (p lipid peroxidation . Thus, the enhanced lipid peroxidation may play a role in the free-radical-induced oxidative damage of some tissues in hypothyroidism. These may show that there is an important relation between hypothyroidism and lipid peroxidation .