Anti CD4 antibodies directly suppress TNF-α production in human Th1 T-cell clones but not IL-4 production in Th2 clones

S Tschiedel; Y Schwitalle; F Emmrich

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Anti CD4 antibodies directly suppress TNF-α production in human Th1 T-cell clones but not IL-4 production in Th2 clones

机译：抗CD4抗体直接抑制人Th1 T细胞克隆中TNF-α的产生，而不抑制Th2克隆中IL-4的产生

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《Arthritis Research》 |2003年第1期|共页
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S Tschiedel; Y Schwitalle; F Emmrich;
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1. Anti CD4 antibodies directly suppress TNF-α production in human Th1 T-cell clones but not IL-4 production in Th2 clones [J] . S Tschiedel, Y Schwitalle, F Emmrich Arthritis Research . 2003,第Suppla1期

机译：抗CD4抗体直接抑制人Th1 T细胞克隆中TNF-α的产生，而不抑制Th2克隆中IL-4的产生
2. Progesterone favors the development of human T helper cells producing Th2-type cytokines and promotes both IL-4 production and membrane CD30 expression in established Th1 cell clones. [J] . Piccinni MP, Giudizi MG, Biagiotti R, The Journal of Immunology: Official Journal of the American Association of Immunologists . 1995,第1期

机译：孕酮促进人类T辅助细胞产生Th2型细胞因子的发展，并促进已建立的Th1细胞克隆中IL-4的产生和膜CD30的表达。
3. Lack of antibody production following immunization in old age:association with CD8~+CD28~- T cell clonal expansions and an imbalance in the production of Th1 and Th2 cytokines [J] . Maria Saurwein-Teissl, Thomas L.Lung, Florentine Marx, The Journal of Immunology: Official Journal of the American Association of Immunologists . 2002,第11期

机译：老年免疫后抗体产生不足：与CD8〜+ CD28〜-T细胞克隆扩增相关，Th1和Th2细胞因子产生不平衡
4. Efficient Selection of Cell Clones with Higher Productivity in the Production of Recombinant Human Monoclonal Antibodies [C] . Ayako Ohshima, Yumiko Takamatsu, Koichi Yamamot, Annual and International Meeting of the Japanese Association for Animal Cell Technology . 2010

机译：在重组人单克隆抗体的生产中有效选择具有更高生产率的细胞克隆
5. Cloning and expression of a biosimilar chimeric monoclonal antibody directed against the human epidermal growth factor receptor and its production in CHO cells for treatment of colo-rectal cancer. [D] . Motiwala, Hatim Maqbulhusen. 2012

机译：针对人表皮生长因子受体的生物仿制药嵌合单克隆抗体的克隆和表达及其在CHO细胞中的产生，用于治疗结肠直肠癌。
6. Anti CD4 antibodies directly suppress TNF-α production in human Th1 T-cell clones but not IL-4 production in Th2 clones [O] . S Tschiedel, Y Schwitalle, F Emmrich 2003

机译：抗CD4抗体直接抑制人Th1 T细胞克隆中TNF-α的产生而不抑制Th2克隆中IL-4的产生
7. In Vivo Inhibition of Anti-Hepatitis B Virus Core Antigen (HBcAg) Immunoglobulin G Production by HBcAg-Specific CD4+ Th1-Type T-Cell Clones in a hu-PBL-NOD/SCID Mouse Model [O] . Cao, Tinghua, Meuleman, Philip, Desombere, Isabelle, 2001

机译：在hu-PBL-NOD / SCID小鼠模型中通过HBcAg特异性CD4 + Th1型T细胞克隆对乙型肝炎病毒核心抗原（HBcAg）免疫球蛋白G的体内抑制
8. Heterogeneity of CD4-Positive Human T-Cell Clones Which Recognize the Surface Protein Antigen of 'Rickettsia typhi' [R] . Carl, M., Vaidya, S., Robbins, F. M., 1989

机译：识别“伤寒立克次体”表面蛋白抗原的CD4阳性人T细胞克隆的异质性

Anti CD4 antibodies directly suppress TNF-α production in human Th1 T-cell clones but not IL-4 production in Th2 clones

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