Depression as the First Manifestation in a Young Girl With Juvenile Systemic Lupus Erythematosus

摘要

Juvenile systemic lupus erythematosus (JSLE) is a multisystem autoimmune disease in which autoantibodies target many body organs, including the central nervous system. Neuropsychiatric manifestations can occur in 22-95% of pediatric cases, but are much less frequent as an initial clinical event, rarely leading to a diagnosis of JSLE.(1-3) Depression can be a symptom of active JSLE or it can occur as a reaction following diagnosis of chronic illness.