Relationship between neutrophil gelatinase-associated lipocalin, cardiac biomarkers, inflammation index and renal parameters in cardiovascular disease

摘要

Paper description:There are few studies examining the contribution of myocardial injury, inflammation severity and impaired renal function to elevated plasma neutrophil gelatinase-associated lipocalin (NGAL) level in myocardial infarction (MI).Patients with MI were evaluated using the corrected values of NGAL, including the NGAL/inflammation index ratio and the NGAL/serum creatinine ratio.The severity of inflammation played a more crucial role than renal and myocardial dysfunction in affecting plasma NGAL levels in patients with MI.Our results may contribute to the evaluation of MI, particularly in patients with concurrent inflammation and renal dysfunction.