Thermodynamic Studies on Electron Donor - Acceptor Interaction of Nano Cobalt Sulphate with 4-imino-1- phenyl - 3(p-tolyl) -1,4 dihydro-5H-pyrazolo [3,4-d] pyrimidin-5-amine in Mixed N,N-Dimethyl- formamide – Water Solvents

摘要

The complex formation constant for the interaction of any salt with ligand gave important data about the interaction between them. Special interest in applications is the comparison between the behaviors in using bulk (normal) and nano salts. Using nano salts, very fine grains in the nanometer form improve the physical properties of the used salts that can be used in many areas in industry like pharmaceutical and medical branch. Cobalt salts is the main source for B-complex drugs can help us in improving the branch of Vitamins in Medical factories by increasing its physical properties. Using new ligand as shown here introduce to the pharmaceutical science new reagent can help in the using of cobalt salts in manufacturing and application in paints as its color is red and also application in battery factor because its strong electrolyte can easily be applied Condutometric method is easily used, cheap and fast method for following the behaviors of bulk and nano salts in different solvents and solutions.. Among the condutometric models used in thermodynamic parameters evaluation we used Debye-Hückel limiting law to be followed here in this to give results for further discussions. Using new ligand (complexion agent) which is novel in study to follow the solution behaviors for nano cobalt sulphate is interesting and valuable results which many scientists search for them .Stability constants or complex formation constants (Kf) are measured for complexes of nanometric ions of Co+2 with 4-imino-1-phenyl-3(p-tolyl)-1,4 dihydro-5H-pyrazolo[3,4-d]pyrimidin-5-amine (IPPA) by applying the condutometric method. The selectivity between ligand and ions in various systems and thermodynamic parameters of complexation is very interesting to have complete pictures about the behavior of salts in solution. On drawing the relation between molar conductance and the ratio of metal to the ligand concentrations, different lines are obtained indicating the formation of 1:2 and 1:1 (M:L) stoichiometry complexes. The ?H and ?S0 of the complexation reaction in the different H2O -DMF binary mixtures were evaluated by the temperature dependence of the formation constants using a linear least square analysis according to Van’t Hoff equation. The data given here in this work can help for the analytical determination of cobalt ions generally and especially nano cobalt salts in human body environment and coloring materials in food industry.