Ionic liquid/ionic liquid dispersive liquid–liquid microextraction, a new sample enrichment procedure for the determination of hexabromocyclododecane diastereomers in environmental water samples

摘要

In this paper, a new ionic liquid/ionic liquid dispersive liquid–liquid microextraction (IL/IL-DLLME) procedure has been developed for the rapid enrichment and determination of three hexabromocyclododecane diastereomers (α-, β- and γ-HBCD) in environmental water samples prior to rapid resolution liquid chromatography-electrospray tandem mass spectrometry (RRLC-ESI-MS/MS). In the IL/IL-DLLME procedure, two kinds of ionic liquids (ILs), a hydrophobic IL and a hydrophilic IL, were used as an extraction solvent and a disperser solvent, respectively. Some important parameters that might affect the extraction efficiencies were optimized. Under the optimum conditions, the limits of detection could reach 0.12–0.22 μg L?1, and the precisions were 4.1–6.7% (n = 7). The linear range was obtained over the range 1–100 μg L?1 for the total concentration of the three HBCD diastereomers. It was satisfactory to analyze real environmental water samples with the recoveries ranging from 88.0 to 114%. All these facts indicated that the IL/IL-DLLME procedure would be a simple alternative for the rapid enrichment and analysis of pollutants in environmental water samples...