Role of Serum Trypsin Level in Diagnosis and Prognosis of Pancreatitis and Compared with Healthy Subjects of Rajasthan

摘要

Inflammation of pancreas is called pancreatitis. Cell death is induced directly by intracellular trypsin which is very harmful. A im of this study was to find out the role of serum trypsin level in diagnosis and prognosis of pancreatitis. M aterial and metho d s : 200 subjects were selected out of them 100 were selected as study group and 100 were selected as control group and distributed according to their age and sex. Serum trypsin was estimated by sandwich elisa kit method. Result : meantrypsin level was found to be 587.94 ng /ml in male patients group as well as in all male control group. Value of trypsin was 186.28 ng/ml in female patients group and mean serum trypsin level was 696.34 and mean value of serum trypsin in female control group was 206.20. The P value was Highly significant in this group. (P<0.0001). Serum trypsin level was calculated in many other groups and compared with healthy subjects and each and every time the level of serum trypsin was found to be increased in all patients. Conclusion : We came to the conclusion that serum trypsin activity looks specific and can be used for diagnosis of Alcoholic and gall stone pancreatitis.