Antimicrobial Susceptibility Patterns of Enterobacteriaceae Isolated from Stool Samples at a Semi-urban Teaching Hospital

摘要

Enterobacteriaceae cause a wide range of diseases including urinary tract infections, respiratory tract infections, sepsis, and gastroenteritis. They are the most frequently recovered pathogens from clinical samples and have varying susceptibility patterns. The study set out to determine the susceptibility profile of enterobacteriaceae species at the Babcock University Teaching Hospital. Enterobacteriaceae were identified using the Microbact 12A kit (Oxoid UK) and susceptibility was determined with the modified Kirby-Bauer Method in line with CLSI 2014 guidelines. Escherichia coli the main isolate was 100% susceptible to Piperacillin/Tazobactam, 94% susceptible to Amikacin, 76.5% susceptible to both Ampicillin/Sulbactam and Ceftazidime, 70.6% susceptible to Ceftriaxone and Meropenem, 67% susceptible to Ciprofloxacin, 58% Susceptible to Gentamicin and 23.5% susceptible to Amoxicillin/Clavulanic acid. Antibiotic resistance among Enterobacteriaceae is on the rise in Babcock University Teaching Hospital. Measures should be put in place to prevent more resistance and to prevent spread of resistant strains.