Prevalence of soil transmitted helminths and impact of Albendazole on parasitic indices in Kotto Barombi and Marumba II villages (South-West Cameroon)

摘要

This study assessed the actual prevalence of geohelminths and the impact of albendazole on parasitic indices in Kotto Barombi and Marumba II. Stools samples were collected from 420 school children and examined using the Kato-katz faecal technique. Participants were treated with 600 mg of albendazole. Baseline prevalence of infections and mean parasite loads were 26.4% and 6226.9e/g (Ascaris lumbricoides), 31.0% and 252.4 e/g (Trichuris trichiura), and 1.4% and 468.0e/g (Necator americanus). Four children (0.9%) were infected withStrongyloides stercoralis.A significant difference of prevalence was observed between the two villages forA. lumbricoides(P= 0.0001) andT. trichiura(P= 0.0005), and parasite loads forT. trichiura (P= 0.0001). Single infection (T. trichiuraorA. lumbricoides) and double infection (A. lumbricoides - T. trichiura)were more prevalent. Post treatment control showed a decrease of prevalence and mean parasite load to 24.4% and 2969.5e/g (A. lumbricoides), and 24.0% and 112.8e/g (T. trichiura), and 0.0% forN. americanusandS. stercoralis. Efficacy and egg reduction rates were 84.6% and 55.3% (T. trichiura), 82.0% and 52.2% (A. lumbricoides), and 100.0% forN. americanusandS. stercoralis.These results suggest that geohelminths infections remain a serious health problem in school children in Kotto Barombi focus.