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One World, One Health - Veterinary Perspectives

机译:一个世界,一个健康-兽医观点

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Multidisciplinary efforts at global, national and local levels are required for creating One Health for the benefit of our planet, mankind and animals. A plethora of emerging global issues viz., international trade and travel, global warming, rapid population growth, ecotourism, food safety concerns, continuous increase in migration of people from rural to urban areas, and changes in traditional livestock rearing practices to meet the demand of higher animal protein production leading to increased risk of emergence and re-emergence of several zoonotic diseases, and all these factors affect human health. Wrong diagnosis and misdiagnosis causing thousands of deaths everyday worldwide have increased the agony and certainly, require one health approach globally. Increased antimicrobial resistance, extreme variability of RNA viruses, involvement of domestic and migratory birds and wildlife in disease transmission have made the scenario of the spread of zoonotic diseases more complicated than ever before. Moreover, cross-border diseases make the health concept more critical as they cause major economic shutdowns across the countries. These issues have created an urge to control emerging and zoonotic diseases at global, national and regional level at a quicker pace than ever before. Joint venture via a collaborative approach from experts of various fields, laboratories and countries certainly seeks attention for One Health to maintain the global integrity. Regional and local networking systems of various international organizations should make use of the highly sensitive and specific methods, both molecular and serological, including cost effective and pen-side diagnostic methods, to detect pathogens at the earliest. Dearth of antiviral drugs, increased antimicrobial resistance among zoonotic organisms, and inadequate compensation during adoption of stamping out policies have created crisis with respect to disease control and preventive measures. This requires heightened biosecurity measures, disease surveillance and monitoring activities, in addition to judicious vaccination. In this regard, developmental vaccinology, generating a variety of new generation vaccines, and advanced delivery systems require special mention. This review deals with all these aspects, which will be beneficial to create One World, One Health concept
机译:为了使我们的星球,人类和动物受益,创建“一个健康”计划需要在全球,国家和地方各级进行多学科的努力。大量新出现的全球性问题,例如国际贸易和旅行,全球变暖,人口快速增长,生态旅游,食品安全问题,从农村到城市的人口不断增加以及为满足需求而改变的传统牲畜饲养方式较高的动物蛋白产量导致多种人畜共患疾病出现和再出现的风险增加,所有这些因素都会影响人类健康。错误的诊断和误诊导致全世界每天成千上万的死亡,这增加了痛苦,当然,全球都需要一种健康方法。增强的抗药性,RNA病毒的极端变异性,家禽和候鸟以及野生动植物参与疾病传播,使人畜共患疾病的传播比以往任何时候都更加复杂。此外,跨界疾病使健康概念变得更加重要,因为它们引起了整个国家的重大经济关闭。这些问题促使人们以前所未有的速度在全球,国家和地区层面控制新兴和人畜共患疾病。来自各个领域,实验室和国家的专家通过合作方式建立的合资企业当然会引起One Health的注意,以维护其全球诚信。各个国际组织的区域和本地网络系统应利用分子和血清学等高度敏感和特异的方法,包括经济有效的笔侧诊断方法,尽早发现病原体。抗病毒药物的缺乏,人畜共患病生物体内抗微生物药耐药性的提高以及在推行消灭政策过程中的补偿不足,都在疾病控制和预防措施方面造成了危机。除明智的疫苗接种外,这还需要加强生物安全措施,疾病监测和监测活动。在这方面,需要特别提及发展性疫苗学,产生各种新一代疫苗和先进的递送系统。这篇评论涵盖了所有这些方面,这将有助于创建“一个世界,一个健康”的概念

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