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Antibody-Based Biosensors for Detection of Veterinary Viral Pathogens

机译:基于抗体的生物传感器,用于检测兽医病毒病原体

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Improved, cost–effective and rapid diagnostic are highly desirable for detection of veterinary pathogens. They are further desirable for veterinary viral pathogen detection as these pathogens generally cause major ailments in animals. Additionally, there are numerous emerging and re–emerging viral pathogens with many of them being zoonotic, and having public health implications. However, the conventional methodologies for viral detection possess numerous lacunae and, subsequently, they fail to provide the indispensable and timely advantages desired for early diseases intervention. Biosensors offer a lucrative alternative to pathogen detection and their global market is rapidly increasing. Antibody–based biosensors are a class of biosensors with high specificity and have the potential of revolutionizing pathogen detection. They offer numerous advantages over the conventional or molecular methodologies, with the most significant being the option of “on–site” pathogen detection. As of yet, there are limited reports of the application of antibody–based biosensors in veterinary viral detection. However, we feel this technology holds a lot of potential, especially in wake of the recent developments in the areas of antibody–generation, nanotechnology and microfluidics along with the availability of improved antibody immobilization strategies. Consequently, it remains to be seen if biosensors can seize a part of the growing veterinary diagnostics market
机译:改进,具有成本效益和快速诊断对于检测兽医病原体非常重要。它们对于兽医病毒病原体的检测是进一步理想的,因为这些病原体通常在动物中引起重大疾病。此外,还有许多新出现和重新出现的病毒病原体,其中许多是人畜共患病的,并具有公共卫生影响。然而,用于病毒检测的常规方法具有许多缺陷,因此,它们不能提供早期疾病干预所需的必不可少的及时优势。生物传感器为病原体检测提供了有利可图的替代方法,其全球市场正在迅速增长。基于抗体的生物传感器是一类具有高特异性的生物传感器,具有彻底改变病原体检测的潜力。与传统方法或分子方法相比,它们具有许多优势,其中最重要的是“现场”病原体检测的选择。迄今为止,关于基于抗体的生物传感器在兽医病毒检测中的应用的报道很少。但是,我们认为这项技术具有巨大的潜力,尤其是随着抗体生成,纳米技术和微流体技术领域的最新发展以及改进的抗体固定策略的可用性。因此,生物传感器能否抓住日益增长的兽医诊断市场的一部分还有待观察

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