Aphrodisiac and Diuretic Activity of Philippine Wild Higher Basidiomycetes, Ganoderma lucidum (W.Curt.:Fr.) P. Karst., Extract in Male Mice (Musmusculus)

摘要

Based on ethno-mycological studies, the aphrodisiac and diuretic effeGanoderma lucidum, in orally administered male mice was studied in this present work. Mice treated with 250 mg/kg b.w. dosesignificantly showed the shortest mounting latency (56.00 ± 7.55 sec), intromission latency (41.00 ± 4.00 sec), ejaculation l(445.67 ± 57.07 sec), and post ejaculatory pause (413.33 ± 15.31 sec) and recorded the highest number of mounts (9.00 ± 1.00) andintromissions (52.67 ± 4.04). The number of pups and the sex ratio of the offspring were also influenced by the extract. Moreextract enhanced the urinary excretion that appeared to vary with dose. Extractand 7.01 ± 0.19 ml in 250 mg/kg b.w. dose) had higher urine volume when compared to the control (4.77 ± 0.24 ml) and displayehigher diuretic index (1.09 in 100 mg/kg b.w. dose and 1.47 in 250 mg/kg b.w. dose). pH and specific gravity of the urine samplesfound higher in treated mice. This first study proved thatactivity with an influence on sex ratio favoring males and of diuretic activity in male mice