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Analgesic Effect of Meloxicam in Canine Acute Dermatitis – a Pilot Study

机译:美洛昔康对犬急性皮肤炎的镇痛作用-一项初步研究

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A double-blind trial was performed on 12 client-owned dogs suffering from acute and painful dermatitis. Clinically these cases represented pyotraumatic dermatitis and pyotraumatic folliculitis. Six dogs were injected with meloxicam and 6 were given placebo. Signs of pain were recorded on a visual analogue scale before administering the drug. This was repeated over the following 2–3 days. All dogs were treated with cephalexin orally. Six dogs given meloxicam and cephalexin showed an average decrease of pain on day 2 of 28.3%, whereas the 6 dogs given placebo and cephalexin showed an average decrease of pain on day 2 of 8.3%. When compared in the Wilcoxon two-sample test, using change in percent and absolute change, the 2 groups yielded p = 0.026 and p = 0.064 respectively. These findings indicate that meloxicam has an analgesic effect on acute dermatitis in dogs.
机译:对患有急性和疼痛性皮炎的12只客户拥有的狗进行了双盲试验。临床上这些病例代表了创伤性皮炎和创伤性毛囊炎。六只狗被注射了美洛昔康,六只被给予了安慰剂。在给药之前,以视觉模拟量表记录疼痛迹象。在接下来的2到3天内重复进行此操作。所有狗均口服头孢氨苄治疗。六只接受美洛昔康和头孢氨苄的狗在第2天的疼痛平均减轻28.3%,而六只接受安慰剂和头孢氨苄的狗在第二天的疼痛平均减轻8.3%。在Wilcoxon两样本测试中进行比较时,使用百分比变化和绝对变化,两组分别得出p = 0.026和p = 0.064。这些发现表明美洛昔康对狗的急性皮炎具有镇痛作用。

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