Relationship Between Vitamin D Deficiency and Markers of Metabolic Syndrome Among Overweight and Obese Adults

摘要

In recent years, metabolic syndrome, obesity, diabetes and cardiovascular disease has had atremendous elevation growth. Many studies have demonstrated negative correlation between vitamin Ddeficiency and indexes of metabolic syndrome in obese patients. This study was designed to find the relationbetween vitamin D deficiency and markers of metabolic syndrome among overweight and obese adultsreferred to obesity center of Shahid Sadoughi hospital in 2014. Eighty-nine overweight and obese adults (79women and 10 men), who 13 subjects were overweight and 76 subjects were obese were recruited in thiscross-sectional study. Total cholesterol, high-density lipoprotein cholesterol, triglyceride, plasma glucose andvitamin D were measured. IDF criteria were used for identifying subjects with metabolic syndrome.Demographic questionnaire was completed. Statistical analysis was performed using SPSS version 16.0.Fisher exact test, logistic regression, and Spearman correlation coefficient were used. The frequency ofvitamin D deficiency was 93.2%. According to IDF criteria, the frequency of metabolic syndrome was 36%.There was no significant relationship between vitamin D deficiency and metabolic syndrome. Amongmetabolic syndrome indicators, there was a significant direct relationship between vitamin D level with FBS(P=0.013) and SBP (P=0.023). There was no significant relationship between vitamin D deficiency andmetabolic syndrome. Due to the lack of relationship between vitamin D deficiency and metabolic syndrome,small number of participants in this study and very low case of normal vitamin D level, further studies areneeded.