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首页> 外文期刊>Acta Biomedica Scientifica >ФАРМАКОЭКОНОМИКА ПРИМЕНЕНИЯ ГЕПАТОПРОТЕКТОРОВ В ТЕРАПИИ ЛЕКАРСТВЕННОГО ПОРАЖЕНИЯ ПЕЧЕНИ ПОСЛЕ ХИМИОТЕРАПИИ
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ФАРМАКОЭКОНОМИКА ПРИМЕНЕНИЯ ГЕПАТОПРОТЕКТОРОВ В ТЕРАПИИ ЛЕКАРСТВЕННОГО ПОРАЖЕНИЯ ПЕЧЕНИ ПОСЛЕ ХИМИОТЕРАПИИ

机译:药物在化疗后治疗肝毒性药物中的药效学经济学研究

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摘要

One of the major problems of modern oncology drug is liver damage, requiring additional costs for its treatment. The aim of our work was to study medical and economic efficiency of various schemes of hepatoprotective treatment of toxic liver damage. The paper presents the use of pharmacoeconomic studies in the treatment of hepatic drug-induced hepatitis, which occurs after chemotherapy in patients with Hodgkin's lymphoma. The study was conducted in the two comparison groups on a "cost - effectiveness". This method was chosen because it is in effect depending on the process (method), treatment was varied, as well as costs incurred. The unit of the effect of the number of days required for the relief of hepatic failure has been selected. Economic analysis of the work includes not only toxic hepatitis therapy, and treatment of any disease complications such as hepatic encephalopathy. The study revealed that the effectiveness of therapy increased 1.4 times and the economic costs were 51.8 % reduced with hepatoprotective drug "remaxol".
机译:现代肿瘤学药物的主要问题之一是肝脏损伤,需要额外的治疗费用。我们的工作目的是研究各种肝保护性毒性肝损害治疗方案的医学和经济效率。本文介绍了药物经济学研究在治疗肝药性肝炎中的应用,肝炎是由霍奇金淋巴瘤患者化疗后发生的。该研究在两个比较组中以“成本-有效性”进行。选择该方法的原因是它的有效程度取决于处理方法(方法),处理方式的不同以及所产生的费用。已选择减轻肝功能衰竭所需天数的影响单位。工作的经济分析不仅包括毒性肝炎治疗,还包括对任何疾病并发症(如肝性脑病)的治疗。研究表明,使用肝保护药“ remaxol”治疗的功效提高了1.4倍,经济成本降低了51.8%。
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