Chemical Constituents Analysis of the Leaves of Bryophyllum pinnatum by GC-MS

摘要

Chemical constituents by GC/MS analysis of an important medicinal plant, Bryophyllum pinnatum was studied. Despite its rich pharmacological potential, so far the chemical constituentsof the Leaves have not been fully documented. Hence in this study, the phytochemicals from the Bryophyllum pinnatum leaves were extracted with ethanol and subjected to GC/MS analysis. Identification of compounds was done by comparing the chromatogram, peak value of the unknown compound with entries in NIST database. Among the 9 phytochemicals identified, oleic acid constituted the highest percent 26.60%, followed by alpha-D-Glucopyranoside, methyl, 24.83%. Other compounds include n-Hexadecanoic acid, 17.83%, Octadecanoic acid, 14.45%, 3,5-Dihydroxy-6-methyl-2,3-dihydro-4H-pyran-4-one, 6.19%, Benzaldehyde, etc. Oleic acid is used as emollients, small amount of oleic acid is used as an excipient in pharmacy, and consumption of oleate in olive oil has been associated with a decreased risk of breast cancer and reduction of blood pressure. 3,5-Dihydroxy-6-methyl-2,3-dihydro-4H-pyran-4-one has already been reported to posses anticancer activity. Brief analysis of some of the compounds reveals the rich pharmacological potential of this part of the plant and thus justify the use of the Leaves of this plant in the treatment of various diseases.