Routine monitoring of blood pressure during general anaesthesia relies on intermittent measurements with a non-invasive brachial cuff every five minutes. This manuscript provides first experimental evidence that a physiology-based pulse wave analysis algorithm applied to optical data (as provided by a standard fingertip pulse oximeter) is capable of accurately estimating blood pressure changes in-between cuff readings. Combined with the routine use of oscillometric cuffs, the presented novel approach is a candidate technology to increase patient safety by providing beat-to-beat hemodynamic measurements without the need of invasive monitoring procedures.
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