Preliminary Study on 3D printing of PEGDA Hydrogels for Frontal Sinus Implants using Digital Light Processing (DLP) : Current Directions in Biomedical Engineering

摘要

Digital Light Processing (DLP) enables high precision 3D-printing of photopolymers and holds promising potential for patient-specific implant solutions. On the material side, Poly(ethylene glycol) diacrylate (PEGDA) has emerged as an interesting material for use in biomedical applications. For adequate photopolymerization, a photoinitiator and a light absorber are necessary, using welldefined concentrations. This study shows preliminary results of DLP 3D-printing of different PEGDA hydrogel compositions with varying water content (90; 70; 50; 30; 10; 0 % w/w) as well as varying concentrations of a photoinitiator and a light absorber. Printing performance and accuracy are investigated by printing rectangular test samples as well as an anatomically customised tubular frontal sinus implant prototype. For basic mechanical characterisation, the hardness of the printed hydrogels is investigated using a Shore A durometer. The results show a decrease in printing accuracy and hardness with an increasing water content of the composition. There is a need to use a light absorber to reach high printing accuracy. This leads to a need for increasing photoinitiator concentration and prolonged light exposure to achieve proper printing performance.