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Parametrization of activation based cardiac electrophysiology models using bidomain model simulations

机译:基于双域模型仿真的基于激活的心脏电生理模型的参数化

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Eikonal models are useful to compute approximate solutions of cardiac excitation propagation in a computationally efficient way. In this work the underlying conduction velocities for different cell types were computed solving the classical bidomain model equations for planar wavefront propagation. It was further investigated how changes in the conductivity tensors within the bidomain model analytically correspond to changes in the conduction velocity. The error in the presence of local front curvature for the derived eikonal model parametrization were analyzed. The conduction velocity simulated based on the bidomain model was overestimated by a maximum of 10%.
机译:Eikonal模型可用于以高效计算的方式计算心脏激发传播的近似解。在这项工作中,通过求解平面波前传播的经典双域模型方程,计算了不同细胞类型的潜在传导速度。进一步研究了双域模型内电导率张量的变化如何解析地对应于传导速度的变化。分析了导出的Eikonal模型参数化存在局部前曲率时的误差。基于双畴模型模拟的传导速度最高被高估了10%。

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