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Spike sorting: the overlapping spikes challenge

机译:峰值排序:重叠峰值挑战

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When recording action potentials (spikes) from many neurons simultaneously via multichannel micro-electrodes the overlapping of spikes from different neurons is a demanding problem for detection and classifi-cation of spikes (spike sorting). Since multichannel electrodes provide better possibilities to separate the superimposed waveforms, we refined an algorithm for separation of overlapping spikes for the use on multichannel recordings and tested it on simulated data with different numbers of signal channels and with several signal parameters. We show that the larger the number of signal channels the better the separation that may be achieved, especially under demanding recording conditions.
机译:当通过多通道微电极同时记录来自许多神经元的动作电位(尖峰)时,来自不同神经元的尖峰的重叠对于尖峰的检测和分类(尖峰分类)是一个严峻的问题。由于多通道电极为分离叠加波形提供了更好的可能性,因此我们改进了用于分离重叠尖峰的算法,以用于多通道记录,并在具有不同数量的信号通道和多个信号参数的模拟数据上对其进行了测试。我们表明,信号通道的数量越大,可以实现的分离效果越好,尤其是在要求苛刻的记录条件下。

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