Effect of Distant Groups on the Enantioselectivity in Kinetic Resolution of isec/i-Alcohols Catalyzed by Microbial Lipases

摘要

A short series of racemic phenoxyalkyl-alkycarbinols, possessing perturbing groups at different distances from the stereogenic center, was prepared. The sec-alcohols (±)-1-phenoxy-2-hydroxybutane (6), (±)-1-phenoxy-3-hydroxyhexane...