Response to “A clinical trial is a success, not a failure, if it does not demonstrate efficacy or does identify safety concerns,” by Simon Kolstoe, Hugh Davies, and Janet Messer

摘要

Kolstoe et al. [1] o?ered a contribution to the archive literature byreminding us that what is termed a failure in the common vernacular ofclinical trials is potentially a success in that negative results can o?er afoundation for what not to do, what does not work, or what is not safe,and thus what to avoid.