Abnormal dynamical coupling between brain structures is believed to be primarilyresponsible for the generation of epileptic seizures and their propagation. In this study, weattempt to identify the spatio-temporal interactions of an epileptic brain using a previouslyproposed nonlinear dependency measure. Using a clustering model, we determine the averagespatial mappings in an epileptic brain at different stages of a complex partial seizure. Resultsinvolving 8 seizures from 2 epileptic patients suggest that there may be a fixed pattern associatedwith regional spatio-temporal dynamics during the interictal to pre-post-ictal transition.
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