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Correlation between actual survival and Tokuhashi and tomita scores in spine metastases

机译:脊柱转移瘤的实际生存与Tokuhashi和tomita评分之间的相关性

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OBJECTIVE: To evaluate the accuracy of the scores of Tokuhashi and Tomita and the actual survival of patients with vertebral metastases.METHODS: A retrospective assessment of 45 patients with spinal metastases. Thirty-one patients underwent surgical treatment and adjuvant therapy and 14 received conservative treatment (chemotherapy/radiotherapy) or palliative/supportive, depending on the scores of Tokuhashi and Tomita.RESULTS: In the study, 80% of patients were female and the mean age was 57.8 years (SD=11.3 years). The most frequent primary tumors were breast and prostate (68.9%). The accuracy of Tokuhashi scale was 53.4% and the Tomita, 64.5%. The concentration of Tomita range of correct classification was in the category of survival 12 months (57.8%), while the Tokuhashi scale presented some adjustment in the other categories, 6 months (15.6%) and 6 to 12 months (2.2%). The histological type of the primary tumor was the only variable that statistically influenced the survival time of patients (p0.001), and patients with lung or liver tumor (most aggressive) presented a risk of death 9.89 times higher than patients with primary tumors of breast or prostate (less aggressive) (95% CI: 3.10 to 31.57).CONCLUSION: The Tokuhashi and Tomita scores showed good accuracy with respect to the actual survival of patients with tumor metastasis in the spine.
机译:目的:评估Tokuhashi和Tomita评分的准确性以及椎骨转移患者的实际生存率。方法:回顾性评估45例脊柱转移患者。结果:在本研究中,有31位患者接受了外科手术和辅助治疗,其中14位接受了保守治疗(化学疗法/放射疗法)或姑息/支持疗法,具体取决于德桥和富​​田的得分。结果:在该研究中,有80%的患者为女性且平均年龄是57.8年(SD = 11.3年)。最常见的原发肿瘤是乳腺癌和前列腺癌(68.9%)。德桥量表的准确度为53.4%,富田秤的准确度为64.5%。正确分类的富田范围集中在生存期大于12个月的类别中(57.8%),而德桥量表在其他类别中的调整范围则小于6个月(15.6%)和6到12个月(2.2%) 。原发性肿瘤的组织学类型是统计学上影响患者生存时间的唯一变量(p <0.001),肺或肝肿瘤(最具侵袭性)患者的死亡风险比原发性肿瘤患者高9.89倍。乳腺癌或前列腺癌(侵略性较低)(95%CI:3.10至31.57)。结论:Tokuhashi和Tomita评分在脊柱肿瘤转移患者的实际生存率方面显示出良好的准确性。

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