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Successful neuroendoscopic treatment of intraventricular brain abscess rupture

机译:神经内镜治疗脑室内脓肿破裂

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Intraventricular rupture of a brain abscess is still associated with a high mortality rate. Here, we report such a case in a patient with normal immunity that was treated successfully using neuroendoscopic approach. A 69-yearold man who had presented with headache and fever developed confusion and restlessness. Magnetic resonance imaging revealed a mass with ring enhancement extending to the right ventricle. Emergency aspiration of cerebrospinal fluid (CSF) from the spinal canal revealed severe purulent meningitis. Bacterial culture of the CSF and blood was negative. Because of prolonged consciousness disturbance, the patient underwent evacuation of the intraventrcular abscess using a neuroendoscope. The pus was centrifuged and collected for bacterial culture, and this revealed Streptococcus intermedius/milleri. After implantation of a ventricular catheter, gentamicin sulfate was administered twice a day for 9 days. Cefotaxime sodium was also administered intravenously for 14 days, followed by oral administration of cefcapene pivoxil hydrochloride for 10 days. The patient made a complete recovery, and was discharged 31 days after admission. After 20 months of follow-up, he is doing well and has returned to his work. In cases of intraventricular rupture of a brain abscess, a neuroendoscopic approach is useful for evacuation of intraventricular debris or septum, and identification of the causative bacterium for selection of antibiotics, possibly reducing the period of hospitalization.
机译:脑脓肿的脑室内破裂仍与高死亡率相关。在这里,我们报告了这种情况,该患者免疫力正常,已使用神经内镜方法成功治疗。一名出现头痛和发烧的69岁男人出现了混乱和不安。磁共振成像显示肿块具有延伸至右心室的环增强。从椎管紧急抽吸脑脊液(CSF)显示严重化脓性脑膜炎。脑脊液和血液的细菌培养均为阴性。由于长期的意识障碍,患者使用神经内窥镜对脑室内脓肿进行了疏散。将脓液离心并收集用于细菌培养,这表明中间链球菌/中间菌。植入心室导管后,每天两次给予硫酸庆大霉素,持续9天。头孢噻肟钠也静脉内给药14天,然后口服头孢卡培酮匹罗西尔盐酸盐10天。患者完全康复,入院后31天出院。经过20个月的随访,他的状况良好,已恢复工作。在脑脓肿的脑室内破裂的情况下,神经内窥镜检查方法可用于清除脑室内的碎片或隔膜,并鉴定出用于选择抗生素的病原细菌,这可能会缩短住院时间。

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