Letter: High-Risk Factors in Symptomatic Patients Undergoing Carotid Artery Stenting With Distal Protection: Buffalo Risk Assessment Scale (BRASS)

摘要

The cytotoxic and mutagenic effects of radiation might explain this increased risk. If the radiation dose delivered is too high, the normal cells will simply die and have no opportunity to become neoplastic. Animal and clinical studies have demonstrated that there is an increasing rate of secondary neoplasm development up to a maximum dose between 3 and 10 Gy, followed by a decrease in risk as the dose increases beyond this range.