A Business Impact Study of the Use of a Supersaturated Calcium Phosphate Oral Rinse (SCPOR) in the Prevention and Treatment of Oral Mucositis

摘要

Oral mucositis (OM) is an inflammation of mucous membranes in the mouth with symptoms ranging from redness to severe ulcerations and pain. It is a condition that affects as many as 45,000 Canadian cancer patients annually, and around 70% of patients undergoing conditioning therapy for bone marrow transplantation (BMT). Almost all patients receiving radiation therapy to the head and neck areas develop OM. Basic oral care is often not enough to reduce the duration or severity of OM in cancer patients. The author conducted a business impact study for Canadian hospitals and cancer centres of the use of~( )a prescription, supersaturated, calcium phosphate, oral rinse (SCPOR) in the prevention and treatment of oral mucositis that occurs due to high-dose chemotherapy in bone marrow transplant patients as well as in head and neck cancer patients receiving radiation therapy. Treatment of OM with the SCPOR for BMT patients not only provided positive, clinical results but net savings of $1,585 for a return on investment of 238.3%. The minimal net savings per head and neck cancer patient, a patient who would also be receiving clinically better care for OM, would be $663 for a return on investment of 49.8%.