“Indefinite for Dysplasia” in Barrett’s Esophagus: Inflammation and DNA Content Abnormality are Significant Predictors of Early Detection of NeoplasiaOpen

摘要

Background:Dysplasia arising from Barrett’s esophagus precedes esophageal adenocarcinoma (EAC). Cases that are difficult to diagnose as dysplastic, especially in the setting of inflammation, may be designated “indefinite for dysplasia (IND).” Although flow cytometric analysis of DNA content has shown some promise in detecting EAC, there are few reports that have specifically evaluated the outcome of IND.