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首页> 外文期刊>Circulation journal >Impact of Rotational Atherectomy on Heavily Calcified, Unprotected Left Main Disease – The New Tokyo Registry –
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Impact of Rotational Atherectomy on Heavily Calcified, Unprotected Left Main Disease – The New Tokyo Registry –

机译:旋磨术对严重钙化,未保护的左主干病变的影响–新东京登记处–

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Background:There is little data on percutaneous coronary intervention (PCI) using rotational atherectomy (Rota) for severely calcified unprotected left main (ULM) lesions.Methods?and?Results:Between January 2005 and August 2011, 64 consecutive patients who underwent drug-eluting stent implantation using Rota were retrospectively evaluated. Of these, 54.7% and 20.3% patients had diabetes and were undergoing hemodialysis (HD), respectively. The mean EuroSCORE and SYNTAX score was 5.6 and 35.4, respectively. Procedural success, defined as residual stenosis <30%, was achieved in 95.3% of patients without fatal complications. Periprocedural myocardial infarction occurred in 7.8% patients. At the 1-year follow up, cardiac death was observed in 6.3% of patients, and target lesion revascularization (TLR) and TLR in the main branch (TLR-MB) were required in 18.8% and 10.9% patients, respectively. Optimal stent expansion was achieved in the majority of 33 patients with available intravascular ultrasound (IVUS) data. However, 5 of 9 HD patients who underwent IVUS required TLR-MB despite optimal stent expansion. The rate of TLR-MB was significantly lower in the non-HD patients than in the HD patients (2.1% vs. 46.2%; P=0.003).Conclusions:PCI using Rota for calcified ULM lesions might guarantee high procedural success and a low complication rate. Although acceptable results were obtained at the 1-year follow up for non-HD patients, the rate of TLR-MB was considerably high for HD patients despite optimal stent expansion. (Circ J 2014; 78: 1867–1872)
机译:背景:采用旋转斑块旋切术(Rota)对严重钙化无保护的左主干(ULM)病变进行经皮冠状动脉介入治疗(PCI)的资料很少。方法和结果:2005年1月至2011年8月之间,连续64例接受了药物治疗的患者回顾性评估使用Rota洗脱支架的情况。其中,分别有54.7%和20.3%的患者患有糖尿病并接受血液透析(HD)。 EuroSCORE和SYNTAX的平均得分分别为5.6和35.4。在没有致命并发症的患者中,有95.3%的患者获得了定义为残余狭窄<30%的手术成功率。 7.8%的患者发生了围手术期心肌梗塞。在1年的随访中,观察到6.3%的患者死于心脏死亡,分别需要18.8%和10.9%的患者分别需要靶病变血运重建(TLR)和主分支(TLR-MB)中的TLR。 33例可获得血管内超声(IVUS)数据的患者中,大多数实现了最佳支架扩张。然而,尽管支架扩张最佳,但接受IVUS的9例HD患者中有5例仍需要TLR-MB。非HD患者的TLR-MB发生率显着低于HD患者(2.1%vs. 46.2%; P = 0.003)。结论:PCI使用Rota治疗钙化性ULM病变可确保高手术成功率和低并发症发生率。尽管对于非HD患者,在1年的随访中获得了可接受的结果,但尽管支架扩张最佳,但对于HD患者,TLR-MB的发生率仍然很高。 (Circ J 2014; 78:1867–1872)

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