首页> 外文期刊>Circulation journal >Morphological Changes and Device Migration After Stent Graft Insertion ― Clinical Application of an Image-Based Modeling System and Analysis With Geometric Parameters ―
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Morphological Changes and Device Migration After Stent Graft Insertion ― Clinical Application of an Image-Based Modeling System and Analysis With Geometric Parameters ―

机译:支架植入后的形态变化和器械迁移―基于图像的建模系统的临床应用和几何参数分析―

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Background: Previously, we developed an image-based modeling system (V-Modeler) to investigate geometric changes in stent grafts (SGs) following their implantation for abdominal aortic aneurysms (AAAs). The aims of the present study were to improve this system for clinical use, to chronologically analyze postoperative morphological changes in SGs, and to demonstrate scenarios of SG migration. Methods?and?Results: Contrast-enhanced computed tomography data from 36 patients who underwent endovascular aneurysm repair (EVAR) for AAAs were used, with 72 centerline paths, in total, analyzed for bilateral SG legs. The existing V-modeler system was modified by introducing a penalty term, optimizing the number of control points using Akaike’s information criterion, and changing the degree of the function from 3 to 5. Geometric parameters were then analyzed immediately, as well as >1 year after EVAR. Eight migrations were found and although overall SG curvature and curvature at the distal (leg) site did not change, curvature at the proximal (trunk) site of SGs decreased over time. Subanalysis revealed that SGs with severe curvature showed the same trend, whereas distal curvature increased in the non-severe curvature group. In addition, proximal curvature decreased more in Excluder than Zenith devices. Conclusions: The present study demonstrates SG behavior after implantation with numerical values for SG length and curvature.
机译:背景:以前,我们开发了一种基于图像的建模系统(V-Modeler),以研究植入支架用于腹主动脉瘤(AAAs)后支架植入物(SGs)的几何变化。本研究的目的是改善该系统的临床应用,按时间顺序分析SG的术后形态变化,并演示SG迁移的情况。方法和结果:对比分析了36例接受AAA血管内动脉瘤修复(EVAR)的患者的CT数据,共分析了72条中心线,以分析双侧SG腿。通过引入惩罚项,使用Akaike的信息准则优化控制点的数量并将功能的程度从3更改为5,对现有的V-modeler系统进行了修改。然后立即对几何参数进行了分析,并且分析了> 1年在EVAR之后。发现了八次迁移,尽管总的SG曲率和远端(腿)部位的曲率没有变化,但SG的近端(躯干)部位的曲率随着时间的推移而下降。亚分​​析显示,具有严重曲率的SG表现出相同的趋势,而在非严重曲率组中远端曲率增加。此外,与Zenith装置相比,Excluder中的近端曲率下降幅度更大。结论:本研究证明了植入后SG的行为,并带有SG长度和曲率的数值。

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