The research undertaken during November 2008 - April 2009 was aimed to find the required pharmacological reference parameters in order to diagnosis the resistance phenomenon of equine strongyls. Strongyls eggs originated from a total of 126 faecal samples collected during the 6 months of study on three different areas of the Danube Delta, where it is estimated that there are a number of over 4,000 wild untreated equine. Testing effectiveness of Mebendazole (MBZ), Fenbendazole (FBZ) and Ivermectine (IVM) was performed in vitro by larva development assay (LDA). To Fenbendazole the reference lethal concentrations were LC50 0.0089g/ml; LC90 -0.7430g/ml and LC100 -0.9265g/ml with a MIC of -18.6031g/ml. To Mebendazole the reference lethal concentrations were LC50 -0.0078g/ml, LC90 -0.4566g/ml and LC100 -0.5688g/ml with a MIC of 21.4542g/ml. To Ivermectine the reference parameters were LC50 -0.00028g/ml, LC90 0.0011g/ml and LC100 0.0013g/ml with a MIC of -250.004g/ml.
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