EVALUATION OF THE IMMUNE RESPONSE INDUCE BY PORCILIS APP AND AN INACTIVATE VACCINE AGAINST PIG PLEUROPNEUMONIA

摘要

Pleuropneumonia is one of the most important bacterial diseases of the respiratory tract of the pig and occurs in most pig-keeping countries (2, 4, 5). Its importance derives from the fact that it can cause pneumonia that results in death, clinical disease may become chronic or subclinical disease in successive batches of pigs and can causes losses from death, reduced production, and increased costs of medication or vaccination.The goal of our research was to compare the following two vaccines used to prevent pig pleuropneumonia:-an inactivate autovaccine, adjuvantated produced by us, representing bacterine group-a subunit vaccine (PorcilisAPP) produced by Intervet, Holand, different by the first vaccine through composition. It contains only the antigenical factors involved in pathogenesis purified toxins (capsular polysaccharides and lypopolysaccharides) and outer membrane proteins (OMP).