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首页> 外文期刊>Brazilian Journal of Microbiology >Draft genome sequence of a multidrug-resistant beta-lactamase OXA-357-producing Acinetobacter pittii ST865 clinical isolate from China
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Draft genome sequence of a multidrug-resistant beta-lactamase OXA-357-producing Acinetobacter pittii ST865 clinical isolate from China

机译:来自中国的多药耐药性β-内酰胺酶OXA-357产生的匹氏不动杆菌ST865临床分离株的基因组序列草案

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摘要

Worldwide increasing emergence of carbapenem-resistant Acinetobacter spp. has rendered the limited availability of effective antimicrobial agents and has become a major public health concern. In this study, we report the draft genome sequence of A. pittii TCM156, a multidrug-resistant isolate that harbored the bla OXA-357 gene. The genome sequence was further analyzed by various bioinformatics methods. The genome size was estimated to be 3,807,313 bp with 3508 predicted coding regions and G + C content is 38.7%. These findings have raised awareness of the possible emergence of OXA-type enzyme-producing A. pittii isolate in China.
机译:耐碳青霉烯的不动杆菌属在世界范围内的出现越来越多。有效抗菌剂的供应有限,并已成为主要的公共卫生问题。在这项研究中,我们报告了A. pittii TCM156(具有bla OXA-357基因的耐多药分离株)的基因组序列草案。基因组序列通过各种生物信息学方法进一步分析。基因组大小估计为3,807,313 bp,具有3508个预测的编码区,G + C含量为38.7%。这些发现提高了人们的认识,即在中国可能会出现OXA型酶生产皮氏杆菌。

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