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Recent Advances in the Understanding of Adiponectin and Its Role in the Aetiology and Pathogenesis of Childhood Obesity

机译:脂联素及其在儿童肥胖病因和发病机制中的作用的最新研究进展

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Obesity is a contemporary disease of epidemic proportions according to national and international reports, considered as the consequence of consumerism and life style modifications, which is both true for developed as well as developing countries. Several reports have shown that 30-35% of the population in developed countries is obese or overweight. Numerous studies have reported the etiology and pathogenesis of obesity, under the possible molecular mechanisms of this condition. One of the main molecules studied is adiponectin, considered as a key adipokine. The present work attempts to review the current knowledge on adiponectin and its participation in the etiology and pathogenesis of childhood obesity.
机译:根据国家和国际报道,肥胖是当代流行病,被认为是消费主义和生活方式改变的结果,无论发达国家还是发展中国家都如此。一些报告显示,发达国家人口中30%至35%是肥胖或超重。在这种病的可能分子机制下,许多研究报告了肥胖的病因和发病机理。研究的主要分子之一是脂联素,被认为是关键的脂肪因子。目前的工作试图回顾当前有关脂联素及其参与儿童肥胖病因和发病机制的知识。

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