BEAT? the bispecific challenge: a novel and efficient platform for the expression of bispecific IgGs

Pierre Moretti; Darko Skegro; Romain Ollier; Paul Wassmann; Christel Aebischer; Thibault Laurent; Miriam Schmid-Printz; Roberto Giovannini; Stanislas Blein; Martin Bertschinger

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BEAT? the bispecific challenge: a novel and efficient platform for the expression of bispecific IgGs

机译：击败？双特异性挑战：表达双特异性IgG的新型高效平台

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《BMC proceedings.》 |2013年第s6期|共页
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Pierre Moretti; Darko Skegro; Romain Ollier; Paul Wassmann; Christel Aebischer; Thibault Laurent; Miriam Schmid-Printz; Roberto Giovannini; Stanislas Blein; Martin Bertschinger;
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中图分类医药、卫生;
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1. Tethered-variable C-L bispecific IgG: an antibody platform for rapid bispecific antibody screening [J] . Kim Hok Seon, Dunshee Diana Ronai, Yee Angie, Protein engineering design & selection: PEDS . 2017,第9a10期

机译：TETHERED-变量C-L BISPECIFIC IgG：用于快速双特异性抗体筛选的抗体平台
2. Enlarging the repertoire of therapeutic monoclonal antibodies platforms: domesticating half molecule exchange to produce stable IgG4 and IgG1 bispecific antibodies [J] . Yang Xiaoyu, Ambrogelly Alexandre Current opinion in biotechnology . 2014,第Null期

机译：扩大治疗性单克隆抗体平台的范围：驯化半分子交换以产生稳定的IgG4和IgG1双特异性抗体
3. Enlarging the repertoire of therapeutic monoclonal antibodies platforms: domesticating half molecule exchange to produce stable IgG4 and IgG1 bispecific antibodies [J] . Yang Xiaoyu, Ambrogelly Alexandre Current opinion in biotechnology . 2014,第Null期

机译：扩大治疗性单克隆抗体平台的范围：驯化半分子交换以产生稳定的IgG4和IgG1双特异性抗体
4. The BEAT? Bispecific Antibody Technology Platform: Designed for Versatile, Robust and Rapid Product Development [C] . Stanislas Blein, Sonia Letestu, Greg Elson, PEGS . 2015

机译：节拍？双特异性抗体技术平台：专为多功能，强大，产品开发而设计
5. A novel approach to control and regulate the classical complement pathway: Highly specific inhibition of C1q globular head binding to human IgG using an engineered single chain antibody variable fragment; recruiting C1q to HER2 /neu positive cells using truncated bispecific antibodies [D] . Hwang, Hee Young 2007

机译：一种控制和调节经典补体途径的新方法：使用工程化的单链抗体可变片段高度特异性地抑制C1q球头与人IgG的结合；使用截短的双特异性抗体将C1q募集到HER2 / neu阳性细胞
6. BEAT® the bispecific challenge: a novel and efficient platform for the expression of bispecific IgGs [O] . Pierre Moretti, Darko Skegro, Romain Ollier, 2013

机译：BEAT®双特异性挑战：表达双特异性IgG的新型高效平台
7. BEAT® the bispecific challenge: a novel and efficient platform for the expression of bispecific IgGs [O] . Pierre Moretti, Darko Skegro, Romain Ollier, 2013

机译：BEAT®双特异性挑战：表达双特异性IgG的新型高效平台

BEAT? the bispecific challenge: a novel and efficient platform for the expression of bispecific IgGs

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