Mesoporous bioactive glasses: Relevance of their porous structure compared to that of classical bioglasses

摘要

In the last decade, the development of third generationbioceramics for Bone Tissue Regeneration has experiencedsignificant progress with the emergence of anew generation of nanostructured materials named mesoporousbioactive glasses (MBG). This new generation ofmaterials, also known as “templated glasses”, presentschemical compositions similar to those of conventionalbioactive sol–gel glasses and the added value of an orderedmesopore arrangement. This article shows an indepthcomparative study of the ordered porous structuresof MBGs compared to conventional glasses (melt and solgel)andhowthese properties influence the bioactivity process.Moreover, the possibility to tailor the textural andstructural properties of these nanostructured materials byan exhaustive control of the different synthesis parametersis also discussed. A brief overview regarding the possibilityof using these materials as controlled drug deliverysystems and as starting materials for the fabrication of 3Dscaffolds for bone tissue regeneration is also given.