This article approaches some general guidelines for evaluating clinical research (design, execution and reporting), including the initial research "idea" (or question to be answered), "hypothesis and objective" which should be aligned with the "primary variable" to be investigated and the "conclusions" reached on the basis of the results of the study. One cannot forget that the study "title" should reflect the "idea" and relative "objective" of the study and the "conclusion", emphasizing the "Magic Sextet of Research".
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