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Assessment of vitamin D and its association with cardiovascular disease risk factors in an adult migrant population: an audit of patient records at a Community Health Centre in Kensington, Melbourne, Australia

机译:评估成年移民人口中的维生素D及其与心血管疾病危险因素的关系:澳大利亚墨尔本肯辛顿社区卫生中心对患者记录的审计

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Background Vitamin D deficiency is a global public health problem associated with increased risk of cardio-metabolic diseases and osteoarthritis. Migrants with dark skin settled in temperate climates are at greater risk of both vitamin D deficiency and cardiovascular diseases. This study aims to identify the risk of vitamin D deficiency and associations with cardiovascular disease in a migrant population in Australia. Methods An audit was carried out at a Community Health Service in Kensington, Melbourne which, services a large migrant population. Data from the clinical records of all adults who visited the medical centre at least once during the period from 1st January 2010 to 31st December 2012 was extracted. The future (10?year) coronary heart disease risk was estimated using Framingham Risk Score. Results The centre has given higher priority to vitamin D testing in migrants, those middle-aged, females and those with diabetes and osteoarthritis. Migrants from countries located in lower latitude regions (Latitude N230 to S230) were 1.48 (95% C.I. 1.32-1.65) times more likely to develop vitamin D deficiency post migration and 0.44 (95% C.I. 0.31-0.62) times less likely to have a >15% 10-year risk of coronary heart disease when compared to their Australian-born counterparts. Conclusions Adherence to a high risk strategy for vitamin D testing was observed in the centre. Pre-migration latitude is an important factor for vitamin D deficiency (lower the latitude higher the risk) and in predicting future risk of cardiovascular disease in migrants. These findings suggest that a targeted approach for vitamin D testing, including zone of origin might better identify individuals at higher risk of both vitamin D deficiency and cardiovascular disease.
机译:背景技术维生素D缺乏症是一个全球性的公共卫生问题,与心血管疾病和骨关节炎的风险增加有关。在温带气候下定居的深色皮肤移民面临维生素D缺乏症和心血管疾病的更大风险。本研究旨在确定澳大利亚移民人口中维生素D缺乏症的风险以及与心血管疾病的关系。方法在墨尔本肯辛顿的社区卫生服务处进行了审计,该服务为大量移民提供服务。从2010年1月1日至2012年12月31日至少去过医疗中心一次的所有成年人的临床记录中提取数据。使用Framingham风险评分估算未来(10年)的冠心病风险。结果该中心对流动人口,中年人,女性以及患有糖尿病和骨关节炎的人的维生素D检测给予了更高的重视。来自低纬度地区(Latitude N23 0 至S23 0 )国家的移民迁移后出现维生素D缺乏症的可能性高1.48倍(95%CI 1.32-1.65)与在澳大利亚出生的同龄人相比,在10年内患冠心病的风险高> 15%的可能性要低0.44(95%CI 0.31-0.62)倍。结论在该中心观察到坚持维生素D测试的高风险策略。迁徙前的纬度是造成维生素D缺乏(纬度越低风险越高)和预测移民中心血管疾病未来风险的重要因素。这些发现表明,针对维生素D的针对性检测方法(包括来源区域)可能会更好地识别处于维生素D缺乏症和心血管疾病风险较高的人群。

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