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Twenty‐year study of in‐hospital and postdischarge mortality following emergency general surgical admission

机译:紧急普外科入院后院内和出院后死亡率的二十年研究

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en Background Emergency general surgery (EGS) patients have a higher mortality than those having elective surgery. Few studies have investigated changes in EGS‐associated mortality over time or explored mortality rates after discharge. The aim of this study was to conduct a comprehensive, population‐based analysis of mortality in EGS patients over a 20‐year time frame. Methods This was a cross‐sectional study of all adult EGS admissions in Scotland between 1996 and 2015. Data were obtained from national records. Co‐morbidities were defined by Charlson Co‐morbidity Index, and operations were coded by OPCS‐4 classifications. Linear and multivariable logistic regression models were used to evaluate changes over time. Results Among 1?450?296 patients, the overall inpatient, 30‐day, 90‐day and 1‐year mortality rates were 1·8, 3·8, 6·4 and 12·5 per cent respectively. Mortality was influenced by age at admission, co‐morbidity, operation performed and date of admission (all P??0·001), and improved with time on subgroup analysis by age, co‐morbidity and operation status. Medium‐term mortality was high: the 1‐year mortality rate in patients aged over 75?years was 35·6 per cent. The 1‐year mortality rate in highly co‐morbid patients decreased from 75·1 to 57·1 per cent over the time frame of the study (P??0·001). Conclusion Mortality after EGS in Scotland has reduced significantly over the past 20?years. This analysis of medium‐term mortality after EGS admission demonstrates strikingly high rates, and postdischarge death rates are higher than is currently appreciated.
机译:背景技术紧急普外科(EGS)患者的死亡率高于择期手术。很少有研究调查随时间变化的EGS相关死亡率或探索出院后死亡率。这项研究的目的是在20年的时间范围内对EGS患者的死亡率进行基于人群的全面分析。方法这是一项横断面研究,研究了1996年至2015年期间苏格兰所有成人EGS入院者。数据来自国家记录。合并症由查尔森合并症指数定义,手术由OPCS-4分类编码。线性和多变量逻辑回归模型用于评估随时间的变化。结果在1 450到296例患者中,住院总死亡率,30天,90天和1年死亡率分别为1%,8%,3·8、6·4和12·5%。死亡率受入院年龄,合并症,进行手术和入院日期的影响(所有P 0·001),并且随着年龄,合并症和手术状态的亚组分析,死亡率随时间而提高。中期死亡率很高:75岁以上患者的1年死亡率为35.6%。在研究期间,高合并症患者的1年死亡率从75%降低至57%(1%)(P?<?0·001)。结论在过去20年中,苏格兰进行EGS手术后的死亡率已大大降低。 EGS入院后对中期死亡率的分析显示出惊人的高死亡率,出院后的死亡率高于目前的预期水平。

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