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首页> 外文期刊>Biomedical Optics Express >Model for measurement of water layer thickness under lipid bilayers by surface plasmon resonance
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Model for measurement of water layer thickness under lipid bilayers by surface plasmon resonance

机译:表面等离子体共振测量脂质双层下水层厚度的模型

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A multilayered-substrate model is proposed for surface plasmon resonance (SPR)-based measurement of the thickness of a water layer sandwiched between a lipid bilayer and an underlying support. To calculate sensitivity, a 473 nm-wavelength excitation source and a silver layer are used for the SPR sensor. It is theoretically shown that the multilayered substrate design achieves sufficient sensitivity for such measurements and that sensitivity is enhanced with a SiO2 layer of appropriate thickness and a buffer solution of high refractive index.
机译:提出了一种多层基质模型,用于基于表面等离振子共振(SPR)的脂质双分子层和下层支持物之间的水层厚度测量。为了计算灵敏度,SPR传感器使用了一个473 nm波长的激发源和一个银层。从理论上讲,多层基板设计可为此类测量获得足够的灵敏度,并且通过使用适当厚度的SiO2层和高折射率的缓冲溶液可提高灵敏度。

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