Nanofiber membranes from cellulose triacetate for chiral separation

摘要

Nanofiber membranes and molecularly imprinted nanofiber membranes were prepared from cellulose triacetate (CTA) by electrospray deposition. CTA nanofiber membrane incorporated l-G1u in preference to d-G1u from racemic mixture of Glu. Z-L-Glu molecularly imprinted nanofiber membranes showed adsorption selectivity toward the enantiomer, of which absolute configuration was same as that of the print molecule. Adsorption isotherms revealed that specific adsorption sites toward l-G1u were found in the control CTA nanofiber membrane and the Z-L-Glu molecularly imprinted CTA one (CTA-L). The affinity constant between l-G1u and specific adsorption site in the control CTA nanofiber membrane was determined to be 3.8 × 10~3mol~(-1)dm~3 and that for CTA-L one to be 7.9 × 10~3 mol~(-1) dm~3, respectively. The control CTA nanofiber membrane selectively transported d-G1u. The perm-selectivity for the CTA nanofiber membrane was determined to be 1.47. Those nanofiber membranes gave high flux values, and the molar mobility for those was over 1.0 × 10~(-8) mol cm cm~2J~(-1)h~(-1).