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An age-structured SIR epidemic model with fixed incubation period of infection

机译:具有固定感染潜伏期的年龄结构SIR流行病模型

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This paper is devoted to the study of an age-structured SIR epidemic system on the basis of the model of polycyclic population dynamics of susceptible, infected and recovered individuals. This model was considered as a nonlinear competitive system of three initial boundary value problems for the nonlinear transport equations with non-local integral boundary conditions and discrete time delay (fixed incubation period of infection). It was obtained the explicit recurrent formulae for computing the traveling wave solution of such system provided the model parameters (coefficients of equations and initial values) satisfy the restrictions that guarantee the existence and uniqueness of continuous solution. Using some insignificant simplifications the age-structured SIR model was reduced to the nonlinear autonomous system of delay ODE. It was studied the dimensionless indicators and conditions of existence of trivial disease-free equilibrium, two non-trivial endemic equilibriums for the incurable and curable infection-induced diseases, respectively. By carrying out an analysis of the local asymptotical stability of the solution of such system we obtain the restrictions for the time delay that guarantee the stability of Solutions in the neighborhood of equilibriums. The numerous simulations of dynamics of SIR population illustrate the results of theoretical analysis. (C) 2017 Elsevier Ltd. All rights reserved.
机译:本文基于易感,感染和康复个体的多环种群动态模型,致力于研究具有年龄结构的SIR流行病系统。对于具有非局部积分边界条件和离散时间延迟(感染的固定潜伏期)的非线性输运方程,该模型被视为具有三个初始边值问题的非线性竞争系统。只要模型参数(方程系数和初始值)满足保证连续解的存在和唯一性的约束,就可以得到用于计算该系统行波解的显式递推公式。使用一些微不足道的简化,将年龄结构的SIR模型简化为延迟ODE的非线性自治系统。研究了无量级无疾病平衡和存在的无量纲指标和条件,分别针对了不可治愈的和可治愈的感染引起的疾病的两个非平常的地方性平衡。通过对此类系统解的局部渐近稳定性进行分析,我们获得了对时延的限制,从而保证了平衡附近解的稳定性。 SIR种群动力学的大量模拟说明了理论分析的结果。 (C)2017 Elsevier Ltd.保留所有权利。

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